April was born as the second of four children and raised by a farming family in Columbus, Ohio.
Grey's Anatomy, Season 6Edit
Alongside Charles, Reed and Jackson, April arrives at Seattle Grace following the merger but ultimatly becomes a victim of the beurocracy when she is fired after making a mistake that claimed a patient's life, meaking her the second resident to fall to the merger after Izzie Stevens.
She is eventually rehired when Derek Shepherd becomes Chief, but helps him administativly until he helps her overcome her fear of treating patients. She develops a crush on Derek. She is present during the Seattle Grace Mercy West Shooting, where her friend Reed is killed.
Grey's Anatomy, Season 7Edit
In the aftermath of the shooting, April and Jackson both move into Meredith's house and lose their outsider status as a consequence of their shared trauma. As one of the people aware of Meredith's miscarriage, April bonds with Meredith which illicits envy in Lexie, who's friendly rivalry with April is resumed. The residents soon learn that April is still a virgin, but after feeling ashamed for some time she finally fights back and tells them all that it isn't something she talks about. She begins to develop feelings for Alex only for the attraction to turn physical, something which April quickly rebuffs not wanting to rush into her first time, leading him upsetting her and ending her crush on him. Bailey ultimatly tells her to wait for the right guy, something which she takes to heart.
April joins Alex, Meredith, Jackson and Cristina in the race of Chief Resident and is immediatly underestimated by her peers and written off. She soon develops a friendship with the new peadeatric attending Robert Stark when she begins to see a different side to the exterior he puts out. Robert eventually asks her out on a date but she turns him down and April agrees even though she feels nothing for him and instead only wants to be his friend.
When the other residents begin teasing her and making her aware of Robert's different intentions for their date she is forced to tell him that she isn't interested in him romantically, resulting in Robert turning personally and professionally cold towards her.
However, ultimatly it is Robert's recommendation that makes Owen consider her in the running for Chief Resident. Her extremly ordered approach to patient care eventually prevails and she is named the new Chief Resident, leaving her somewhat of a pariah amongst her unsucsessful peers.
Grey's Anatomy, Season 8Edit
As the new Chief Resident, April struggles in her responsibilities and finds the other residents are quick to ignore her authority. She soon begins to question why she was chosen, especially when a task in which the residents working together to save a patient sees Jackson emerge as the natural leader of the group, and believes herself to be a bad Chief Resident when she uses the residents competitive nature to get them to take her rules seriously, but Callie soon assures her that she was simply knowing her peers. When Jackson's mother arrives in Seattle she makes April realize that she needs to losen up and encourages her to have sex, something which April takes in her stride. She develops a new sense of confidence which helps her confront her fellow residents, especially Alex, and remind them that, while they may not respect her, she is in charge and going against her rules will have consequences.
After Meredith and Derek gained custody of Zola, April moves out of their home with Jackson and, despite her reluctance, Alex. Like the rest of her fellow residents, she soon begins to feel the pressure of her upcoming board exams and she and Jackson started to act as each other's study partners. With the end of their fifth year approaching April, like the other residents, begins applying for post-residency positions at other hospitals but soon learns that, while they were impressed with her resume some interviewers were put off by her intense persona. When the time comes for the residents to take the board exams, April heads to San Fransisco with the rest of the residents but the stress becomes too much for her.
She ends up sleeping with Jackson, losing her virginity to him, but regrets her actions the following day. As she and Jackson prepare to take their exams, she admits that she was a virgin because she loves Jesus and now Jesus hates her. April's crisis of conscience severely affects her examination, especially when she reveals to Jackson that she's concerned because she enjoyed breaking her promise. She and Jackson sleep together again during an interval in the exam, leading April to tell her examiners that she loves Jesus and, even though he isn't listening anymore, she isn't going to hide that.
Ultimately, however, she learns that she has failed the exam. As her residency comes to an end, her lack of board certification lead all of her job prospects to vanish including her future at Seattle Grace when Owen revokes his job offer and she is left without a post-residency position at any hospital.
Grey's Anatomy, Season 9Edit
April fulfills her contract at Seattle Grace, and her final days there coincide with the discovery of the plane crash. Her relationship with Jackson remains uncertain and, on her last day at Seattle Grace, they intend to meet but as Jackson is held up dealing with Mark's injuries, April leaves for Ohio without talking to him.
However, after Mark's death months later, Owen arrives at the farm and offers April her job back, saying he should have been a better teacher to her. April sees her reinstatement as a second chance and tries to "revirginize", something which upsets Jackson upon her return to SGMW. However, passions stir between the two once again and they resume sleeping together. April struggles with balancing her feelings for Jackson and her faith, a situation which comes to a head when April believes herself to be pregnant. Jackson steps up and they decide to get married if she is pregnant, but April's relief at the negative result insults Jackson and they ultimately break up.
April struggles to let go of her feelings for Jackson, especially when she hears that he is dating Stephanie Edwards although this news helps her accept a date from a paramedic, Matthew Taylor, who shows an interest in her after they meet in the ER.
Grey's Anatomy, Season 10Edit
April is very reserved romantically and spent most of her adult life as a virgin. Her romantic naivety often shines through, showcased through her brief attractions to both Derek Shepherd and Alex Karev, both of which were one-sided. She has however experienced unrequited attraction from another angle with Robert Stark, who's interest in April wasn't reciprocated. She has since developed a complex relationship with her best friend Jackson Avery after she lost her virginity to him, leading the two to realize their feelings for each other. However, Jackson's imminent departure from Seattle and the implosion of April's own career left their romantic future uncertain.
Kepner is a competent doctor although she has been fired from Seattle Grace Mercy West Hospital on two separate occasions. She, along with Izzie Stevens, where victims of the merger as April was fired soon after her hospital merged with Seattle Grace, due to an oversight of hers costing a patient her life. She was, however, rehired by Derek Shepherd when he became Chief. After initially struggling with resuming her life as a surgeon and hiding behind clerical work to avoid making another fatal mistake, Kepner soon returned to the O.R. She also caught the attention of trauma attending Owen Hunt and began to develop as a trauma surgeon, with Kepner eventually choosing to specialise in the field.
She was named Chief Resident of her class and initially struggled with commanding respect, but soon came into her own as a leader. However, her success would be short lived as personal complications prevented her from passing her board exams. Her career took a hit as she found hospital's weren't willing to hire her without board certification, Seattle Grace included. For a second time, Owen fired her from Seattle Grace leaving her future uncertain.
However, Owen would ultimately rehire her in an attending position, despite the fact she remains board uncertified. April's focus returned to trauma surgery, something plagued by the closure of Seattle Grace's E.R closure. However, when the E.R reopened as part of Grey Sloan Memorial Hospital April was able to continue pursuing trauma as a speciality.
- Sarah Drew also portrayed another character, seperate from April, Judy in two episodes of Private Practice