"Go It Alone" is the twentieth episode of the tenth season of Grey's Anatomy and the 216th produced episode of the series. It is also the 327th produced episode of the Grey's Anatomy franchise. It was broadcast on April 17, 2014.
It's the day before the Harper Avery awards and Cristina turns to Meredith for help writing her acceptance speech but remains adamant that she's attending the awards alone as the pressure of the ceremony begins to mount. However, when several of her patients find themselves in critical condition, Cristina is forced to put her own doubts aside for the good of her patients after a family's fight endangers the health of their children. Elsewhere, Derek finds himself struggling to balance parenthood, teaching and his presidential appointment while, having decided to have a second child, Callie and Arizona try to decide which of them will get pregnant. Meanwhile, the residents find themselves pulling an all-nighter while, when Jackson struggles to understand the wishes of a deaf patient's parents who refuse a cochlear implant for their child, it sparks an argument with April about their future, children and religion and Alex deals with the physical and emotion strain off moonlighting at a private practice.
- "Surgery is a solo act. We step up to the table with a scalpel in our hand and we go it alone. The isolation can start to define you because, even though you're surrounded by a team what it really comes down to is your training, your choices, your wits, your hands, your stitch. It comes down to just you"
- "Surgeons are trained to go it alone, to be solo artists, to be mavericks in and out of the O.R. But the truth is we are never alone. We stand on the shoulders of those who came before us. We stand side by side with the colleagues who have supported us, prepared us, for the moment that every surgeon lives for... when it all comes down to your training, your choices, your wits, your hands, your stitch. When it all comes down to you."
- "Holiday" - Capital Cities
- "Every Little Thing She Does Is Magic" - Sleeping At Last
- "Something About You" - Cary Brothers feat. Laura Jansen
- "Everybody Wants To Rule The World" - Aron Wright
This episode's title originated from the song Go It Alone, originally sung by Beck.