Grey's Anatomy, Season 12
Season No.
September 24, 2014 - May 19, 2016
No. Of Episodes
DVD Release
August 30, 2016
Season Twelve of Grey's Anatomy initially aired on September 24, 2014 with the premiere episode and ended on May 19, 2016 with the season finale on ABC. The season comprises of 24 episodes.


Plot PointsEdit


Principle CastEdit

Season twelvefeatured 16 actors appearing in a starring billing. All season eleven cast members returned for the twelfth year with the exception of Patrick Dempsey who ended an eleven year run as Derek in the previous season finale. After guest starring in 30 episodes over the past five years, Jason George was elevated to main cast status as Ben Warren.

Martin Henderson joined the cast as Nathan Riggs as of the season's seventh episode while Giacomo Gianniotti joined the main cast after a guest starring in 10 episodes across Season 11 and 12.

* Credited from "The Me Nobody Knows" onward
** Credited from "The Sound Of Silence" onward, recurring beforehand



Episode number: 01
Original air date: September 24, 2015
Plot: Three months later, Meredith struggles with her new living arrangements after moving back into her old house with Amelia and Maggie as, back at the hospital, Callie is forced to step up for a patient and become her advocate when the case of two young girls it by a train reveals a tragic reality while Bailey is unnerved when a candidate for the vacant Chief of Surgery position arrives at the hospital and her credentials force Bailey to question whether she has what it takes to be the Chief. Meanwhile, Arizona tries to find a new room mate and Jackson seems to be the only person not anticipating April's return from Jordan.
Recurring characters: Giacomo Gianniotti as Andrew DeLuca and Debbie Allen as Catherine Avery

Walking Tall

Episode number: 02
Original air date: October 1, 2015
Plot: On her first day as Chief of Surgery, the pressure mounts for Bailey as she strives for perfection, but she soon realizes the struggles of being a leader when she pushes her attending too far when faced with a deadly pituitary gland tumour on a woman who has grown exceptionally tall while Meredith grows frustrated when she is forced to pick up the slack for the work Bailey left behind. Meanwhile, April is placed in quarantine when she breaks out in a suspisious rash, escalating her marital issues with Jackson while tensions mount between Stephanie and Jo when Jo begins to feel her peers are outshining her. Amelia and Owen struggle to navigate their romantic waters while Arizona learns that Callie has started dating.
Recurring characters: Giacomo Gianniotti as Andrew DeLuca

I Choose You

Episode number: 03
Original air date: October 8, 2015
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Old Time Rock And Roll

Episode number: 04
Original air date: October 15, 2015
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Guess Who's Coming To Dinner

Episode number: 05
Original air date: October 22, 2015
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The Me Nobody Knows

Episode number: 06
Original air date: November 5, 2015
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Something Against You

Episode number: 07
Original air date: November 12, 2015
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Things We Lost In The Fire

Episode number: 08
Original air date: November 19, 2015
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The Sound Of Silence

Episode number: 09
Original air date: February 11, 2016
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All I Want Is You

Episode number: 10
Original air date: February 18, 2016
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Unbreak My Heart

Episode number: 11
Original air date: February 25, 2016
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My Next Life

Episode number: 12
Original air date: March 3, 2016
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All Eyez On Me

Episode number: 13
Original air date: March 10, 2016
Plot: Bailey, Callie, Meredith, Jackson and Jo travel to a military hospital to perform a risky and revolutionary procedure on a cancer patient and, with the all eyes on them, the pressure mounts as Callie's professional standing is put on the line and Meredith struggles with her friends pushing her to date again. Meanwhile, Ben makes a risky move when he takes drastic action to save a patients life, putting him on a collision course with Richard, while the E.R. is inundated with a cheer leading squad after a stunt goes horribly wrong, forcing Stephanie to reflect on her own teenage years. Elsewhere, Andrew pushes Maggie to go public with their relationship.
Recurring characters: Samantha Sloyan as Penny Blake


Odd Man Out

Episode number: 14
Original air date: March 17, 2016
Plot: Template:Summary/GA12x14

I Am Not Waiting Anymore

Episode number: 15
Original air date: March 24, 2016
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When It Hurts So Bad

Episode number: 16
Original air date: March 31, 2016
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I Wear The Face

Episode number: 17
Original air date: April 7, 2016
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There's A Fine, Fine Line

Episode number: 18
Original air date: April 14, 2016
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It's Alright, Ma (I'm Only Bleeding)

Episode number: 19
Original air date: April 14, 2016
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Trigger Happy

Episode number: 20
Original air date: April 21, 2016
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You're Gonna Need Someone On Your Side

Episode number: 21
Original air date: April 28, 2016
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Mama Tried

Episode number: 21
Original air date: May 5, 2016
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At Last

Episode number: 23
Original air date: May 14, 2016
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Family Affair

Episode number: 24
Original air date: May 21, 2016
Plot: Template:Summary/GA12x24