Meredith is the daughter of the brilliant and famed surgeon Ellis Grey, but her childhood took a backseat to Ellis' career, leading her to endure distant and cold early years. Her mother drove her father, Thatcher Grey, away with her determination and through her affair with Richard Webber, leaving Meredith alone with her distant mother as Thatcher stopped trying to be in his daughter's life and started a new family. After the affair ended, Ellis tried to kill herself and she was saved by Meredith, but the event left her scarred.
After completing her undergraduate degree at Dartmouth College, she backpacked around Europe with Sadie Harris after attending Dartmouth, but eventually came home and decided to attend medical school, something her mother greatly disproved of. She persevered and eventually succeed in completing medical school in spite of Ellis's Alzheimer's diagnosis.
The night before she began her internship at Seattle Grace Hospital, having moved back to Seattle to care for her mother, she met Derek Shepherd and the two had a one night stand although Meredith was determined that was all it would be.
Grey's Anatomy, Season 1Edit
Season 1 Focuses around Meredith and the other interns grappling with the emotional struggles of becoming surgeons. Season 1 also focuses around the interns relationships with each other and the other residents and their learning curves in the OR. Season 1 starts of with Meredith falling for her boss, Derek Shepherd aka McDreamy. McDreamy and Meredith have relationship that is kept hidden for quite awhile as only Cristina Yang, fellow intern and Meredith's best friend, knows.
Cristina and Meredith first join forces in Episode 1 as they team up trying to help a failing patient named Katie. Katie is a pageant girl who has seizures and a hem ridge. When Grey is picked for the best surgeries and this becomes a pattern. The other interns such as Isobel Stevens and George O'Malley and Alex Karev take notice, sprouting their jealousy. Rivalry, relationships and the cut throat events shock their lives as interns.
Meredith's personal life is slowly relieved with flashbacks of her family history. Throughout the first season others personal life is relieved and that all the interns have skeletons in their closests too.
Meredith continues to try to be closed off as her mild temper and beauty intrigues Derek but also runs him amuck as Meredith does not trust Derek. Later in the series, the Love Triangle between Derek, his wife Addison, and Meredith grows into an issue. Other noteworthy relationship in the first season is of Cristina's and Dr. Preston Burke, another intern and attending relationship. Burke's mother leaves Cristina and Meredith tongue tide as she calls out the girls flaws. Cristina and Meredith mutually bond and as both are closed off and determined and not "wear your heart on your sleeve" girls like IZZIE.
Season 1 is the hook for all who love intense storylines, dreams, ambition and love.
Grey's Anatomy, Season 2Edit
Grey's Anatomy, Season 3Edit
Grey's Anatomy, Season 4Edit
Grey's Anatomy, Season 5Edit
Grey's Anatomy, Season 6Edit
During the shooting, Meredith had a miscarriage.
Grey's Anatomy, Season, 7Edit
In the wake of the shooting, Meredith helps hold everyone else together including Cristina and Derek, hiding her own pain from her peers. She isn't cleared for surgery by Dr. Perkins until she tells Derek about her miscarriage. She helps Cristina through her PTSD but becomes annoyed when Derek and Cristina bond over their shared trauma after Cristina quits the programme. Cristina eventually reveals that she blames Meredith for her PTSD as she wouldn't have operated if it wasn't Meredith's husband leaving their friendship strained. However, when Cristina returns to the hospital their friendship also mends. She and Derek then begin trying to start a family but she soon learns that she miscarried because of her 'hostile uterus' and they may have trouble conceiving.
She soon learns that she is in the running for Chief Resident but her fertility troubles interfere with her professional life. She soon joins Derek on his Alzheimer's clinical trial after Derek realizes how invaluable her experiences with the disease is. She is offered to continue her mother's work on diabetes in the form of clinical trial with the Chief. However, she turns it down to remain on the Alzheimer's trial, stating that she only wants to cure her mother's disease. Meredith and Derek continue in their quest to get pregnant when Meredith begins to take fertility drugs but soon enough they begin to have side effects when she loses her eyesight in the O.R. She is ordered to stop taking the drugs and their fertility issues continue at the expense of her career.
When Adele Webber is diagnosed with Alzheimer's she begins to see the impact this is having on Richard. After Adele confused her for Ellis, Meredith makes a risky move to ensure that Adele gets the active agent and not the placebo, something only known to Alex. Hiding her secret, she finds her personal and professional lives moving forward as she and Derek attempt to adopt an African orphan named Zola, getting legally married in the process, and the race for Chief Resident heats up. Alex eventually reveals her secret to Owen and she is forced to face the repercussions, still demanding that she did what was best for Adele and would do it again.
Grey's Anatomy, Season 8Edit
Season 8 starts out with Meredith getting fired for messing with the medical trial she and Derek were working on. This concerns the social worker who is helping them adopt Zola. Meredith steals Zola in fear of her being taken from Meredith which causes high alarms. After being returned Zola is taken away but is then returned to her and Derek who's relationship is reinstated. Season 8 features Meredith as a 5th year resident which is the last year of surgical residency in Seattle Grace Mercy West. Meredith soon through the season realizes she wants to continue her mother's work and be a general surgeon. Meredith passes the board and finishes her residency along with her fellow friends and residents (excluding April Kepner). The season 8 finale shows Meredith in a plane crash on the way to pick up organs with Cristina, Arizona, Derek, Mark and Lexie. Lexie who is Meredith's half sister dies when she is stuck under the back of the plane after Mark confesses his love for her. This is a major heartbreak for Meredith as she has begun to feel her as a great sister since her introduction in season 3. They are stranded for almost 2 weeks until they are rescued. Derek hurt his hand badly. Arizona had her leg amputated so she now has a prosthetic. Mark died next season after being on life support for 30 days.
Grey's Anatomy, Season 9Edit
Meredith is a fellow general surgeon in season 9. She receives new interns known as Shane Ross, Jo Wilson, Stephanie Edwards and Leah Murphy. Meredith chooses Jo to perform the intern surgery which is an appendectomy (removal of appendix). After the plane crash Meredith has some emotional trauma and mourns the loss of her sister Lexie Grey as well has friend Mark Sloan. Meredith and Derek move in to the new house that he built along with Owen Hunt, Mark Sloan, Jackson Avery and Ben Warren. Cristina has moved to Minnesota but Meredith continues to face chat her who is to scared to get on a plane and come home. Eventually she does overcome her fear and return to Seattle as a Cardiothoracic surgeon. Deeper in to the season Meredith discovers she is pregnant with her second child. She surprises Derek by giving him a shirt for Zola that says best big sister. Meredith was concerned because she had been told she has had a hostile uterus since her miscarriage in Season 6. During the super storm in the season 9 finale Meredith gives birth to a baby boy. Meredith has to have a C-Section which is performed by Shane Ross who has trouble and almost kills Meredith because he can't control the bleeding. Eventually Meredith is saved by Dr. Miranda Bailey. When Meredith gets to hold her baby she decides to name him Derek Bailey Shepard. Miranda of course is elated and wants to spend as much time with "Bailey" as possible. The super storm does continue into Season 10.
Grey's Anatomy, Season 10Edit
Grey's Anatomy, Season 11Edit
Grey's Anatomy, Season 12 Edit
Grey's Anatomy, Season 13 Edit
Meredith has a romantic bond with the world class surgeon Dr. Derek Shepherd since the beginning of the show, they had a one night stand the night before she began her internship at Seattle Grace Hospital. She refuses to go out with him in the beginning because he is her boss and it is highly inappropriate.
Meredith is devastated when, at the end of the first season, Derek's wife, Addison, showed up at the Hospital. It is later revealed that they were separated because Addison cheated on Derek with his friend, Dr. Mark Sloan. After Addison gives Derek the divorce papers, he decides to try to rebuild their marriage, leaving Meredith heartbroken.
When Derek doesn't choose her over his wife, Meredith begins to have a series of one night stands, including one with Dr. George O'Malley who had feelings for her since he first met her.
After Addison and Derek's efforts to rebuild their marriage begin to fail, Derek and Meredith have sex and Addison finds Meredith's panties in Derek's tuxedo pocket, finally putting an end to their marriage.
Meredith was dating a veterinarian, Finn Dandridge, when she had sex with Derek. Derek tells her she has a choice to make. Meredith is fed up with trying to decide so she begins to date them both. Meredith later decides to choose Derek, but before she could say anything, he decides that Finn is a better man for Meredith and walks away.
They later reconcile but once again break-up because Meredith is unable to commit to their relationship. Derek begins dating a nurse, Rose, but he and Meredith decide they are meant to be later on in the season and make-up after their clinical trial reaches success. She builds Derek a house of candles, showing she can commit.
In the next season Derek has a rough patch with a patient, showing his "Dark Side", he makes her a couple of marriage proposals that were unsatisfying, but later they decide to get married, the ceremony doesn't happen because they give it to their close friends, Dr. Isobel Stevens and Dr.Alex Karev. They get married on a post-it.
After Meredith and Derek discover that Meredith has medical issues with conceiving children they decide to adopt a baby, Zola, that came from Africa for a surgery in a program that was organized by Dr. Alex Karev. In order to adopt they decide to get legally married.
When they get the baby Derek finds out Meredith tampered with their clinical trial to help Dr. Richard Webber's wife, Adele, who was presenting with Alzheimer's. They are briefly separated but later on reconcile after their baby is taken away from them when the adoption agency representative finds out they were separated and that Meredith lost her job (for a brief amount of time) putting their parenting into question. Derek is still a angry at Meredith but at the middle of the season they manage to get their baby back and become happy again.
After the plane crash on the seaosn 8 finale, Meredith helps Derek to deal with his injured hand, encouraging him to get it fixed and calling his sisters to see if they would donate nerves for a surgery. Derek describes Meredith as not being "Dark and Twisty" anymore, he says now she is "Optimistic". In the beginning of season nine Meredith also reveals she is pregnant and is able to deal with her insecurities because of the risks of her pregnancy. Currently on the show Derek had surgery on his hand and is operating normally and Meredith is in the second trimester of her pregnancy.
In the beginning of her internship Meredith is described by the Chief of Surgery as being just like her mother, an extraordinary surgeon. She always appeared to be a good intern, she won a competition for the "Sparkle Pager" that would give her an opportunity to get to participate in many surgeries.
She passed her intern exams and began to develop an interest for Neuro, but she had to stop because it was deeply affecting her marriage with Dr. Derek Shepherd, her husband and mentor. She spent some time delivering babies but after being called attention by the new chief, Dr. Owen Hunt as he suspected she was "sinking", she decides to pursue the same specialty as her mother, General Surgery.
With the help of Dr.Richard Webber she convinced Dr. Callie Torres to train her for the Medical Boards and even though she was sick during the examination she passed and decided to be a fellow at Seattle Grace Mercy West Hospital, working alongside with Dr. Richard Webber and Dr. Miranda Bailey.
She is the attending that is most feared by the interns, she is called "Medusa" because as one of her interns said, "She is a monster of mythic proportions". She also appears to be an extraordinary surgeon because in her first year as an attending she was able to remove an extremely rare tumor with no help.