"Save Me" is the eighth episode of the first season of Grey's Anatomy and the 8th produced episode of the series. It is also the 8th produced episode of the Grey's Anaromy franchise. It was broadcast on May 15, 2005.
Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother and Cristina's unexpected pregnancy causes her to struggle to accept a pregnant patients decision to put her baby's life before her own.
- "You know how when you were a little kid and you believed in fairytales. That fantasy of what you're life would be. White dress, Prince Charming who'd carry you away to a castle on a hill. You'd lie in bed at night and close your eyes and you had complete and utter faith. Santa Claus, the Tooth Fairy, Prince Charming: they were so close you could taste them. But eventually you grow up. One day you open your eyes and the fairytale disappears. Most people turn to the thing, and the people, they can trust. But the thing it it's hard to let go of that fairytale entirely because almost everyone still has that smallest bit of hope, of faith, that one day they'll open their eyes and it'll all come true."
- "At the end of the day faith is a funny thing. It turns up when you don't really expect it. It's like one day you realize that the fairytale may be slightly different than what you dreamed. The castle, well, it may not be a castle and it's not so important that it's happy ever after, just that it's happy right now. See once in a while, once in a blue moon, people will suprise you. And once in a while people may even take your breath away."
- "David" - Nellie McKay
- "Feels Like" - Marsha Qrella
- "The Rapture" - Laura Viers
- "I Love The Rain The Most" - Joe Purdy
- "No Illusions" - 78 Saab
- "Fix You Up" - Tegan And Sara
This episodes' title references the song Save Me, originally sung by Queen