"Start Me Up" is the twelfth episode of the seventh season of Grey's Anatomy and the 138th produced episode of the series. It is also the 203rd produced episode of the Grey's Anatomy franchise. It was broadcast on January 13, 2011.
Arizona seeks Mark's advice as she tries to reconcile with Callie, who has big news of her own to share. Meredith and Derek's continue in their attempt to concieve a child and Richard learns of Teddy's decision to marry Henry forcing her to make a life or death decision during his surgery. Meanwhile, on the same day that they learn the race for Chief Resident has begun Meredith, Cristina, Alex, April and Jackson recieve a new crop of first year med students to teach.
- "People are really romantic about the beginnings of things. Fresh start, clean state, a world of possibility. But no matter what new adventure you embark on you're still you. You bring you into every new beginning in your life so how different can it possibly be?"
- "It's all anyone wants, right? Clean slate, a new beginning. Like that's going to be any easier. Ask the guy pushing the boulder up the hill, nothing's easy about starting over. Nothing at all."
- "Cry Baby" - Cee Lo Green
- "Harder Than Easy" - Jack Savoretti
- "England" - The National
This episodes' title references the song Start Me Up, originally sung by The Rolling Stones